The Amide Linkage

An authoritative reference to an important and ubiquitous chemical linkage The amide linkage is one of the most fundamental and widespread chemical bonds in nature, underlying the properties of a vast array of organic molecules, polymers, ...

The Amide Linkage

An authoritative reference to an important and ubiquitous chemical linkage The amide linkage is one of the most fundamental and widespread chemical bonds in nature, underlying the properties of a vast array of organic molecules, polymers, and materials, including peptides and proteins. Arthur Greenberg, Curt Breneman, and Joel Liebman's peerless text provides comprehensive coverage of the experimental, structural, and computational findings that shed light on the chemical and physical properties of the amide linkage, as well as its emerging applications in materials and biotechnology. Chapters in The Amide Linkage highlight how this chemical bond factors in the design of enzyme inhibitors, cyclic peptides, antibacterial agents, and emerging nanotechnology applications. This one-of-a-kind study also: * Discusses selected aspects of chemical reactions, structure, bonding, and energetics of the amide bond, including amide rotational barriers, stereochemistry, complexation, spectroscopy, and thermochemistry * Presents specific applications to supramolecular and stereospecific synthesis * Discusses key aspects of peptide and protein chemistry-such as molecular recognition, conformation, and folding-in terms of the amide linkage * Includes chapters contributed by numerous eminent chemists and biochemists Organic, medicinal, polymer, and physical chemists, as well as biochemists and materials scientists, will find The Amide Linkage to be an invaluable addition to their professional libraries.

More Books:

The Amide Linkage
Language: en
Pages: 653
Authors: Arthur Greenberg, Curt M. Breneman, Joel F. Liebman
Categories: Science
Type: BOOK - Published: 2002-11-11 - Publisher: John Wiley & Sons

An authoritative reference to an important and ubiquitous chemical linkage The amide linkage is one of the most fundamental and widespread chemical bonds in nature, underlying the properties of a vast array of organic molecules, polymers, and materials, including peptides and proteins. Arthur Greenberg, Curt Breneman, and Joel Liebman's peerless
N/(formula) N/(formula) Interactions of the Amide Linkage with N-substituents
Language: en
Pages: 166
Authors: Özlem Demir
Categories: Amides
Type: BOOK - Published: 2002 - Publisher:

Books about N/(formula) N/(formula) Interactions of the Amide Linkage with N-substituents
A Computational Investigation of the Effects of Distortion on the Amide Linkage Using a Series of Small to Medium-sized Bridgehead Bicyclic Lactams
Language: en
Pages: 172
Authors: David Thomas Moore
Categories: Amides
Type: BOOK - Published: 1997 - Publisher:

Books about A Computational Investigation of the Effects of Distortion on the Amide Linkage Using a Series of Small to Medium-sized Bridgehead Bicyclic Lactams
Cyclic Ligands Containing the Amide Linkage and Manganese Macrocyclic Complexes Containing an Azo Group
Language: en
Pages: 308
Authors: El-ssaed Omar Ali Sabbak
Categories: Azo compounds
Type: BOOK - Published: 1977 - Publisher:

Books about Cyclic Ligands Containing the Amide Linkage and Manganese Macrocyclic Complexes Containing an Azo Group
Antisense Drug Technology
Language: en
Pages: 848
Authors: Stanley T. Crooke
Categories: Medical
Type: BOOK - Published: 2007-07-25 - Publisher: CRC Press

Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generation drugs, the book evaluates the technology as